The clinical trial, conducted in partnership with AbbVie, tested a combination of the drug Epkinly and Bristol Myers Squibb’s Revlimid. In patients with diffuse large B-cell lymphoma who had previously undergone at least one round of treatment, the regimen significantly extended the period of progression-free survival compared to standard care.
In section Market Quotes
Genmab Stock Rallies on Positive Lymphoma Trial Results
Shares of Genmab jumped 6% Tuesday after the Danish biotechnology firm reported that a late-stage trial for its lymphoma therapy successfully met its primary endpoint. The result offers a potential breakthrough in blood cancer treatment, positioning the company to challenge established therapies with a chemotherapy-free regimen.

Jefferies analysts noted that these findings match the efficacy benchmarks set by Roche’s Columvi and Lunsumio while providing the added benefit of a chemotherapy-free protocol. Beyond the immediate clinical success, the data lowers the risk profile for potential use as a first-line treatment. Genmab and AbbVie now plan to initiate discussions with global regulatory authorities to determine the path toward market authorization for this specific combination.
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