The conference, held May 24–28 in Lexington, Kentucky, served as a platform for experts to address the biological barriers to conception. Dr. Joanne Kwak-Kim, the university's director of reproductive medicine and immunology and the seventh-ranked clinician-scientist in the field, chaired a session dedicated to innovative immunotherapies. Her team presented findings that explore how the endometrial environment and hormonal shifts impact reproductive success.
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Rosalind Franklin University Researchers Tackle Rising Infertility Rates
With U.S. fertility rates dropping to 1.6—well below the 2.1 replacement threshold—clinicians are turning to immune-mediated solutions. Researchers from Rosalind Franklin University, currently ranked first globally in reproductive immunology, recently unveiled new data on the mechanisms behind pregnancy loss and reproductive failure at the ASRI annual meeting.
Beyond individual presentations, the university showcased extensive clinical research, including a study of 803 women analyzing autoimmune modulation of ovarian reserve and investigations into anti-Müllerian hormone as an immune signaling regulator. These efforts aim to bridge the gap between immune system dysfunction and the decline in annual U.S. births, which have fallen from a 2007 peak of 4.3 million to approximately 3.6 million. Janice Urban, interim executive vice president of research, noted that identifying these specific immune mechanisms is critical for developing future clinical interventions to support successful pregnancies.
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