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Pearl Health Secures $110 Million to Scale AI-Driven Medicare Care

Healthcare technology firm Pearl Health has raised $110 million in a fresh funding round, aiming to accelerate the deployment of its AI platform. The capital, led by Andreessen Horowitz, will support the company’s expansion into Medicare Advantage and the scaling of its risk management tools for providers across the U.S.

Pearl Health Secures $110 Million to Scale AI-Driven Medicare Care

The financing package consists of a $50 million equity round and a $60 million debt facility led by Trinity Capital. This influx of capital comes as Pearl Health reports significant operational momentum, having achieved profitability in 2025. The company currently manages approximately $3.6 billion in annualized medical spend and supports a network of over 10,000 providers across more than 40 states.

Pearl Health focuses on shifting clinical models from reactive treatment to preventative, outcomes-based care. Its AI-driven platform identifies high-risk patients and automates administrative workflows, allowing clinicians to prioritize patient interaction over manual data entry. With this new investment, the company projects it will triple its patient base by the end of 2026 and generate $500 million in gross savings for the healthcare system. The expansion plans include developing sophisticated Care Orchestration agents designed to further streamline tasks like post-discharge follow-ups and wellness visit scheduling.

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