Elysium Health Targets Menopause Symptoms with Longevity Science

The formulation centers on Basis, the company's flagship NAD+ supplement, which recently showed promise in a pilot study published in Frontiers in Aging. Researchers observed that participants experienced significant reductions in hot flashes, sleep disturbances, and bloating after one week of use. The study also noted a shift toward a more favorable estradiol-to-estrone ratio, suggesting that cellular metabolism plays a critical role in how women experience this transition.

Balance expands on this foundation by incorporating S-equol, a soy-derived compound known for its impact on bone health and hot flash frequency, alongside ergothioneine, an antioxidant intended to mitigate oxidative stress. By combining these elements, the company aims to address the systemic decline in health that often accompanies the drop in estradiol levels. According to Marie Migaud, a study co-author and professor at The University of Western Australia, these findings provide a scientific basis for investigating the intersection of NAD+ biology and reproductive aging.

Lynne Chang, vice president of product development at Elysium, emphasized that the transition represents a whole-body biological shift rather than just a collection of symptoms. With women spending approximately 40% of their lives in postmenopause, the product seeks to offer a multi-decade health strategy. The company plans to further validate these findings through upcoming randomized, placebo-controlled clinical trials as it continues to expand its research into reproductive aging.