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Vertex Pharmaceuticals Lifts Revenue Forecast After Crinetics Buyout

A 5% jump in after-hours trading followed Vertex Pharmaceuticals' decision to hike its annual revenue guidance to a range of $13.15 billion to $13.25 billion. The Boston-based company is betting on its $1-billion-plus acquisition of Crinetics Pharmaceuticals to fuel growth despite a recent dip in quarterly profits.

Vertex Pharmaceuticals Lifts Revenue Forecast After Crinetics Buyout

The upward revision accounts for an anticipated $40 million to $50 million in revenue from Palsonify, a hormone treatment gained when the Crinetics deal closed on Sept. 1. While the firm raised its top-line outlook, it simultaneously signaled a rise in operational expenses tied to the integration of these new assets and continued investment in its drug pipeline.

Third-quarter financials revealed a profit decline to $653.6 million, or $2.56 per share, down from $1.08 billion during the same period last year. Total costs ballooned to $2.73 billion as the company ramped up spending on commercial opportunities. Adjusted earnings of $4.76 per share missed the $4.83 consensus estimate from FactSet analysts, even as total revenue climbed 12% to $3.44 billion, bolstered by the company's established cystic fibrosis franchise.

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