Traditional agriculture remains tethered to volatile weather patterns and land availability. By transitioning coffee production to plant cell culture, companies like Coffeesai can bypass these environmental constraints. Brevel’s platform introduces light into the closed fermentation process, a departure from standard dark fermentation that allows for precise control over cell metabolism. This method triggers specific biological responses, boosting the yield of valuable natural compounds that define coffee’s sensory characteristics.
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Brevel Expands Illuminated Fermentation to Coffee Cell Culture
Climate change threatens half of the world's coffee-growing land by 2050, prompting a shift toward lab-grown alternatives. Israel-based biotech firm Brevel is now applying its proprietary illuminated fermentation technology to Coffeesai’s coffee cell cultures, aiming to stabilize production volumes and enhance the flavor profiles of lab-grown biomass.

Brevel recently secured a USD 1 million grant from the Israel Innovation Authority to adapt this infrastructure for plant cell-culture applications. According to CEO Yonatan Golan, the platform has already demonstrated high-density, semi-continuous growth in trials. Coffeesai is currently evaluating these results to determine if the technology can reliably scale to commercial levels. Beyond this partnership, Brevel is extending its reach to other sectors, including collaborations with US-based Ayana Bio and various cocoa cell-culture startups, as it moves to prove the viability of light-driven biology at a 5,000-liter scale.
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