Tampa General Hospital Adopts Rapid Host-Response Sepsis Testing

The implementation follows extensive research conducted by Tampa General and USF Health physicians. In a study of 893 emergency department patients, researchers found that incorporating the host-response technology into existing workflows led to a 26% increase in the reclassification of patients as unlikely to have sepsis. Furthermore, the data showed a 33% reduction in exposure to the antibiotic cefepime and a 13% decrease in hospitalizations for those flagged by sepsis alerts. Preliminary analysis suggests these efficiencies could save approximately $179,000 per 100 patients.

Unlike traditional diagnostics that target specific pathogens, MeMed BV measures three immune-system proteins—TRAIL, IP-10, and CRP—to generate a score reflecting the nature of the infection. This diagnostic capability is now integrated into the hospital’s electronic health record system, providing clinicians with actionable data during the critical early stages of a sepsis alert. This initiative aligns with the hospital's broader strategy, which includes the Sepsis Hub—a data-driven platform developed in partnership with Palantir Technologies to enhance real-time clinical intervention.