Karyopharm Therapeutics has submitted a supplemental New Drug Application to the FDA, aiming to bring its drug XPOVIO in combination with ruxolitinib to patients suffering from myelofibrosis. The company has requested a Priority Review for the therapy, which could compress the regulatory evaluation period to six months.
With over five million downloads and a flat brokerage fee model, the Bengaluru-based trading platform SAHI has earned a place on the Forbes Asia 100 to Watch 2026 list. The firm, operated by Aaritya Broking, stands as the only Indian stock-broking entity recognized in the finance category this year.
Toronto is testing a new AI-driven pre-check system to unclog its residential permitting pipeline. By flagging missing documents and code compliance issues before submission, the city aims to reduce the correction cycles that currently stall thousands of housing projects, drawing on a model that accelerated Honolulu’s permit approvals by over 50 percent.
On August 31, 1976, Vanguard launched the First Index Investment Trust with just $11.3 million in assets, facing widespread skepticism from a market obsessed with picking winners. Today, that experiment stands as a cornerstone of global finance, having transformed how millions of individuals approach long-term wealth accumulation.
With tropical weather system Invest 97L expected to bring heavy rain and gusty winds to Southeast Texas starting Tuesday, CenterPoint Energy has activated its Emergency Operations Center. The utility is staging frontline crews and coordinating with local officials to address potential disruptions to electric and gas services.
Defense Metals Corp. has unveiled assay results from its spring 2026 drilling campaign at the Wicheeda Rare Earth Project near Prince George, Canada, with initial core samples showing high-grade mineralization. The data, drawn from eleven drill holes, are expected to bolster the project's resource classification following a successful infill program.
The global market for transformer monitoring is poised for significant expansion, with projections indicating growth from $3.11 billion in 2026 to $4.98 billion by 2031. Driven by a 9.9% compound annual growth rate, this sector reflects an intensifying focus on grid reliability and the modernization of aging electrical infrastructure.
Burlington-based Labcorp has overhauled its Global Trial Connect platform, integrating new digital tools for sponsors and investigator sites. The update aims to reduce administrative friction in clinical trials by unifying study oversight, supply tracking, and reporting into a single, intuitive interface informed by direct feedback from over 180 global industry partners.
RedHill Biopharma has offloaded its 70% interest in Talicia to Apotex Health Corp. for an initial $18 million in cash. The transaction provides the Raleigh-based company with immediate liquidity as it looks to pivot its commercial strategy toward new, higher-value gastrointestinal product opportunities and long-term operational profitability.
BioLineRx is scaling its clinical efforts for GLIX1, an experimental small molecule for glioblastoma, following promising preclinical data and a strategic pivot toward combination therapies. The Tel Aviv-based firm reported a $4.3 million net loss for the second quarter of 2026 while securing $3.75 million in new capital.
NameSilo Technologies Corp. posted record-breaking financial results for the second quarter of 2026, driven by a 16.6% revenue increase to $18.8 million. The domain registrar saw total bookings surge by 40.7% year-over-year to $22.6 million, even as the company ramped up capital expenditure across its newer technology subsidiaries.
Pulsenmore Ltd. has officially initiated U.S. commercial operations following FDA authorization, marking a strategic pivot for the Israel-based firm. During the first half of 2026, the company recorded its first domestic patient scans and secured key partnerships, even as it navigated a wider net loss compared to the previous year.
Summit Midstream Corporation has reached a final investment decision to expand its Double E pipeline system, targeting a fourth-quarter 2028 completion date. The project, designed to boost forward haul capacity to the Waha Hub by 900 million cubic feet per day, is backed by new long-term shipper commitments.
After three decades navigating the complexities of the pressroom floor, Jay Engels is transitioning to the technical sales team at Provident, LLC. Based in Appleton, Wisconsin, the veteran specialist will oversee support operations across the Midwest and Central Plains, tasked with bridging the gap between hardware manufacturing and chemical performance.
Patients battling both psoriatic disease and obesity saw sustained improvements in skin clearance, joint health, and metabolic markers after one year of combined treatment with Taltz and Zepbound. The results from two Phase 3b trials suggest that tackling immune-mediated inflammation and metabolic dysfunction simultaneously offers a more effective long-term strategy.
To prove its new Detroit-style pizza belongs among legendary fast-food icons, Domino's is bankrolling a $1 million giveaway. The company is inviting customers to trade receipts from competitors like McDonald's or Taco Bell for a free, single-serving 'Domino' pizza to see if it holds its own against established industry staples.
A new PostNet location is set to open its doors in Spring, Texas, on September 9, marking a transition for logistics executive Ron Tish and his family from corporate supply chain management to local business ownership at their new center on Rayford Road.
The distinct flavor profile of Fuji apples paired with a hint of ginger, once a limited-time offering, is now a permanent fixture on store shelves. Red Bull North America officially transitioned its former Winter Edition into the Red Bull Apple Edition, available across the United States starting August 31, 2026.
At Gamescom 2026, TCL has officially stepped into the spotlight as the European monitor and television partner for the upcoming fantasy title Tides of Annihilation. The partnership centers on a public demo in Cologne, where players are testing the game’s combat mechanics on the manufacturer’s latest high-performance display hardware.
Eli Lilly and Company has entered a definitive agreement to purchase Merida Biosciences, a move aimed at bolstering its immunology portfolio with a precision platform designed to eliminate disease-causing antibodies. The deal, valued at up to $2.875 billion, targets a shift away from broad immune suppression toward selective molecular degradation.
With offices in Tacoma and Portland, Suppression Systems, Inc. brings five decades of specialized fire protection experience to Pye-Barker Fire & Safety. The acquisition, finalized August 31, 2026, strengthens the Atlanta-based giant’s reach into mission-critical sectors including data centers, power plants, and marine infrastructure across the Pacific Northwest.
Los Angeles-based private equity firm Levine Leichtman Capital Partners has acquired the Pasadena-based Colt Group, a specialty industrial services provider. The deal, completed in partnership with the existing management team, aims to expand the company’s footprint in the mission-critical infrastructure and asset repair sector.
Svenska Handelsbanken AB has subscribed for 223,677 class C shares in Swedish Orphan Biovitrum AB, marking the completion of a directed share issue. This financial move, authorized by shareholders in May, serves to secure the company’s obligations under its long-term incentive plan for permanent employees.
Aon plc has signed a definitive agreement to acquire insurance brokerage firm USI for $17 billion, a move designed to cement its dominance in the U.S. middle-market segment. The deal, which follows Aon’s 2024 acquisition of NFP, aims to bolster the firm’s data analytics capabilities and expand its reach into the E&S market.
The U.S. Navy has awarded Continuous Composites a Phase II Small Business Innovation Research contract to integrate electrical conductors directly into load-bearing UAV structures. By replacing traditional wire harnesses with 3D-printed conductive pathways, the initiative aims to simplify drone architecture and enhance repairability in demanding field environments.
Nevada King Gold Corp. has added a fourth drill rig to its Atlanta Gold Mine Project in southeast Nevada, signaling an aggressive push to test previously undrilled targets. The company is pivoting its exploration strategy to target the Splay Zone, a high-potential area identified through recent structural reinterpretation.
A coalition of environmental organizations filed a lawsuit in the U.S. Court of Appeals for the 9th Circuit on Friday, challenging the Trump administration's decision to re-register trifludimoxazin. The herbicide, a PFAS-based compound, is now approved for use on major crops despite internal EPA data linking it to cancer.
Tel Aviv-based Meitav Investment House reported total assets under management of NIS 467.5 billion—approximately $153 billion—as of July 31, 2026. This figure represents a 14.3% increase compared to the firm's total holdings at the end of 2025, signaling significant growth for Israel’s largest investment house.
Swedish Orphan Biovitrum AB has completed a directed issue of 223,677 class C shares to Svenska Handelsbanken AB. The move secures the company's ability to fulfill obligations under its long-term incentive scheme for permanent staff, following board approval granted earlier this year to manage these specific equity commitments.
With the frequency of billion-dollar weather events increasing, Denver-based AidKit has introduced a pre-positioned platform designed to eliminate the lag between disaster onset and financial aid distribution. AidKit Ready allows governments and nonprofits to configure compliance, payment, and eligibility workflows well before a crisis forces them to act.
